The novel opens in 1775 with its famous double vision of an age that was both the best and the worst of times, and with a quiet errand: the elderly banker Jarvis Lorry carries the coded message "Recalled to life" to Paris. There he and young Lucie Manette find her father, Doctor Manette, who has been imprisoned without trial in the Bastille for eighteen years and now sits making shoes, his mind half broken. They bring him back to England and slowly back to himself.
Five years later, in London, the lives of the Manettes intertwine with two men who look alike but live unlike: Charles Darnay, an exiled French aristocrat who has renounced his cruel family name, and Sydney Carton, a brilliant but dissipated lawyer who believes he has wasted himself beyond repair. Both love Lucie; she marries Darnay. Carton, hopeless of her, pledges that for her and for anyone dear to her he would do anything, even give his life.
Across the Channel, the novel keeps returning to Saint Antoine, where the Defarges keep a wine-shop and the people starve. The spilt wine staining the street prefigures spilt blood, and Madame Defarge knits the names of the condemned into a register that cannot be erased. Generations of contempt and abuse by the nobility, embodied in Darnay's uncle the Marquis, harden the poor into instruments of revenge. When the Bastille falls, the long-stored fury breaks loose.
Drawn back to Paris by duty to a faithful servant, Darnay is arrested as an emigrant aristocrat. The third book follows the family into the Terror: tribunals, the grindstone, the daily death-carts. Darnay is freed, re-arrested, and finally condemned on the strength of a document written by Doctor Manette himself years before, which records the crimes of Darnay's family against the Defarges' kin. The machinery of justified hatred turns on the innocent.
Sydney Carton redeems his squandered life by quietly taking Darnay's place in the prison and at the guillotine, using their resemblance to free the man Lucie loves. The book closes with his unspoken vision of a peaceful future for the family and with the conviction that what he does is a far, far better thing than he has ever done. Love and self-sacrifice answer the violence without excusing it, and a wasted man is, at the last, recalled to life.