A plague has fallen on Thebes, and the suppliant people gather at the palace begging their king to save them as he once did. Oedipus, who long ago freed the city by answering the riddle of the Sphinx, has already sent Creon to the Delphic oracle. The answer comes back plainly: the land is defiled by the unpunished murderer of the former king, Laius, and Thebes will not be clean until the killer is driven out.
Oedipus throws himself into the hunt with total confidence. He pronounces a public curse on the unknown murderer and on any who shelter him, and he summons the blind prophet Teiresias for help. The seer, unwilling at first, is goaded into speaking and tells Oedipus to his face that he himself is the polluter of the land. The king, enraged, hears this only as a plot hatched by Creon to seize his throne.
Jocasta, queen and wife, tries to calm him by proving that prophecy cannot be trusted. An oracle once doomed Laius to die at his own son's hand, she says, yet Laius was killed by robbers where three roads meet, and the son was left to die as an infant. Her words have the opposite effect. The detail of the three roads stirs a memory in Oedipus of a man he killed on the road from Delphi, and his certainty begins to crack.
The truth is assembled piece by piece, by the very people who hoped to comfort him. A messenger from Corinth arrives with news meant to reassure Oedipus and instead reveals that he was an adopted, found child. An old herdsman, the last witness, is forced under threat to confirm the rest: the infant given away to die was the son of Laius and Jocasta. Oedipus has killed his father and married his mother. Jocasta, who grasped it first, has already gone inside to die.
Jocasta hangs herself, and Oedipus, finding her body, puts out his own eyes with the brooches from her robe. He emerges blinded, begging to be cast out of the city as the curse he himself proclaimed demanded. Creon takes charge and will not yet exile him. The play ends with the Chorus pointing to the fallen king and warning that no mortal should be called happy until he has passed the final boundary of life free from pain.